What are some world issues or ideas that matter to you?

ok this is going to be a little long but oh well. An annual fashion parade is coming up in my area, and it has a "wearable art" section. This pretty much just involves designing a piece of art in the form of a dress, and putting it on show on the catwalk. Almost every year, people choose depressing or similar issues, like pollution (big one!) and whaling. The saddest thing is that they usually win. I was wondering, if I were to design a piece, what are some issues that are important to you that I could do? Even if you have an amazing idea for a design or material? I am open to all G-PG rated suggestions. It doesn't have to have a deep meaning or anything, just ideas on issues and designs. Also, I was thinking about doing a piece on something like the joy of life, just to lighten up the whole affair? I wouldn't win with that, but do you think it would be a good idea just to take away from all the depressing subjects people choose? Thanks for your help if you read all of this :)